POLR3F anticorps (AA 1-270)

N° du produit ABIN7150466

Détail du produit anti-POLR3F anticorps

Antigène: POLR3F (Polymerase (RNA) III (DNA Directed) Polypeptide F, 39 KDa (POLR3F))

Épitope: AA 1-270

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLR3F est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human DNA-directed RNA polymerase III subunit RPC6 protein (1-270AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:2000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur POLR3F

Antigène: POLR3F (Polymerase (RNA) III (DNA Directed) Polypeptide F, 39 KDa (POLR3F))

Autre désignation: POLR3F (POLR3F Produits)

Synonymes: anticorps 2810411G20Rik, anticorps 3010019O03Rik, anticorps 3110032A07Rik, anticorps RPC39, anticorps RPC6, anticorps zgc:56299, anticorps zgc:76983, anticorps RNA polymerase III subunit F, anticorps polymerase (RNA) III (DNA directed) polypeptide F, anticorps POLR3F, anticorps Polr3f, anticorps polr3f

Sujet:

Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct RNA Pol III binding to the TFIIIB-DNA complex. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.

Aliases: DNA directed RNA polymerase III 39 kDa polypeptide antibody, DNA directed RNA polymerase III 39 kDa polypeptide F antibody, DNA directed RNA polymerase III subunit F antibody, DNA directed RNA polymerase III subunit RPC6 antibody, DNA directed RNA polymerases III 39 kDa polypeptide antibody, DNA-directed RNA polymerase III subunit F antibody, DNA-directed RNA polymerase III subunit RPC6 antibody, MGC13517 antibody, Polr3f antibody, Polymerase (RNA) III (DNA directed) polypeptide F antibody, RNA polymerase III 39 kDa subunit antibody, RNA polymerase III C39 subunit antibody, RNA polymerase III subunit C6 antibody, RPC 39 antibody, RPC 6 antibody, RPC39 antibody, RPC6 antibody, RPC6_HUMAN antibody

UniProt: Q9H1D9