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DDIT4 anticorps (N-Term)

DDIT4 Reactivité: Humain, Rat, Souris WB, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN500644
  • Antigène Voir toutes DDIT4 Anticorps
    DDIT4 (DNA-Damage-Inducible Transcript 4 (DDIT4))
    Épitope
    • 15
    • 14
    • 12
    • 8
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 53
    • 22
    • 8
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain, Rat, Souris
    Hôte
    • 64
    • 4
    Lapin
    Clonalité
    • 66
    • 2
    Polyclonal
    Conjugué
    • 27
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DDIT4 est non-conjugé
    Application
    • 45
    • 33
    • 26
    • 13
    • 13
    • 13
    • 8
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects DDIT4 at N-term.
    Réactivité croisée (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Peptide affinity chromatography
    Immunogène
    RTP801 antibody was raised against a 14 amino acid peptide from near the amino terminus of human DDIT4.
    Isotype
    IgG
    Top Product
    Discover our top product DDIT4 Anticorps primaire
  • Indications d'application
    ELISA. Western blot: 2 - 4 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Antigène
    DDIT4 (DNA-Damage-Inducible Transcript 4 (DDIT4))
    Autre désignation
    DDIT4 (DDIT4 Produits)
    Synonymes
    anticorps redd1, anticorps Dig2, anticorps REDD-1, anticorps REDD1, anticorps 5830413E08Rik, anticorps AA415483, anticorps Rtp801, anticorps dig2, anticorps rtp801, anticorps sb:cb821, anticorps zgc:64114, anticorps DNA damage inducible transcript 4, anticorps DNA-damage-inducible transcript 4, anticorps DNA damage inducible transcript 4 S homeolog, anticorps ddit4, anticorps DDIT4, anticorps Ddit4, anticorps ddit4.S
    Sujet
    RTP801 was initially identified as a gene induced by DNA damage, and later found to also be regulated by other cellular stresses such as hypoxia and glucocorticoid treatment. Recently, RTP801 has been shown to act as a mediator of tuberous sclerosis complex (TSC)-dependent regulation of the mammalian Target of Rapamycin (mTOR), an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle. In response to energy stress, RTP801 inhibits mTOR function, resulting in dephosphorylation of downstream targets such as ribosomal protein S6 kinase 1 and 4EBP1 and decreasing cell growth. Disregulation of RTP801 may thus contribute to human tumorigenesis.Synonyms: DDIT-4, DNA-damage-inducible transcript 4, Dig2, HIF-1 responsive protein, Protein regulated in development and DNA damage response 1, REDD-1, REDD1, RTP801
    ID gène
    54541
    NCBI Accession
    NP_061931
    UniProt
    Q9NX09
    Pathways
    Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process
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