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DDIT4 anticorps (N-Term)
DDIT4
Reactivité: Humain, Rat, Souris
WB, EIA
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-DDIT4 anticorps
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Antigène
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DDIT4
(DNA-Damage-Inducible Transcript 4 (DDIT4))
Épitope
Tous les épitopes à travers DDIT4 Anticorps.
N-Term
Reactivité
Toutes les réactivités sur DDIT4 Anticorps
Humain, Rat, Souris
Hôte
Toutes les hôtes sur DDIT4 Anticorps
Lapin
Clonalité
Toutes les clonalités sur DDIT4 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers DDIT4 Anticorps
Cet anticorp DDIT4 est non-conjugé
Application
Tous les applications à travers DDIT4 Anticorps.
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificité
This antibody detects DDIT4 at N-term.
Réactivité croisée (Details)
Species reactivity (tested):Human, mouse, rat
Purification
Peptide affinity chromatography
Immunogène
RTP801 antibody was raised against a 14 amino acid peptide from near the amino terminus of human DDIT4.
Isotype
IgG
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Information d'application
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Indications d'application
ELISA. Western blot: 2 - 4 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Stockage
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Buffer
PBS containing 0.02 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Détails sur DDIT4
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Antigène
DDIT4
(DNA-Damage-Inducible Transcript 4 (DDIT4))
Autre désignation
DDIT4 (DDIT4 Produits )
Synonymes
anticorps redd1, anticorps Dig2, anticorps REDD-1, anticorps REDD1, anticorps 5830413E08Rik, anticorps AA415483, anticorps Rtp801, anticorps dig2, anticorps rtp801, anticorps sb:cb821, anticorps zgc:64114, anticorps DNA damage inducible transcript 4, anticorps DNA-damage-inducible transcript 4, anticorps DNA damage inducible transcript 4 S homeolog, anticorps ddit4, anticorps DDIT4, anticorps Ddit4, anticorps ddit4.S
Sujet
RTP801 was initially identified as a gene induced by DNA damage, and later found to also be regulated by other cellular stresses such as hypoxia and glucocorticoid treatment. Recently, RTP801 has been shown to act as a mediator of tuberous sclerosis complex (TSC)-dependent regulation of the mammalian Target of Rapamycin (mTOR), an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle. In response to energy stress, RTP801 inhibits mTOR function, resulting in dephosphorylation of downstream targets such as ribosomal protein S6 kinase 1 and 4EBP1 and decreasing cell growth. Disregulation of RTP801 may thus contribute to human tumorigenesis.Synonyms: DDIT-4, DNA-damage-inducible transcript 4, Dig2, HIF-1 responsive protein, Protein regulated in development and DNA damage response 1, REDD-1, REDD1, RTP801
ID gène
54541
NCBI Accession
NP_061931
UniProt
Q9NX09
Pathways
Neurotrophin Signaling Pathway , Regulation of Carbohydrate Metabolic Process
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