PARP16 anticorps (AA 120-170) (Alexa Fluor 680)

N° du produit ABIN5008361

Détail du produit anti-PARP16 anticorps (Alexa Fluor 680)

Antigène: PARP16 (Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16))

Épitope: AA 120-170

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PARP16 est conjugé à/à la Alexa Fluor 680

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PARP16

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PARP16

Antigène: PARP16 (Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16))

Autre désignation: PARP16 (PARP16 Produits)

Synonymes: anticorps PARP16, anticorps zgc:77744, anticorps ARTD15, anticorps C15orf30, anticorps pART15, anticorps BC055447, anticorps C79952, anticorps PARP-16, anticorps LRRGT00109, anticorps RGD1306243, anticorps poly(ADP-ribose) polymerase family member 16, anticorps poly(ADP-ribose) polymerase family member 16 L homeolog, anticorps poly (ADP-ribose) polymerase family, member 16, anticorps PARP16, anticorps parp16.L, anticorps parp16, anticorps Parp16

Sujet:

Synonyms: C15orf30, Chromosome 15 open reading frame 30, EC 2.4.2.30, FLJ25281, PAR16_HUMAN, PARP 16, PARP-16, Parp16, Poly ADP ribose polymerase family member 16, Poly [ADP ribose] polymerase 16, Poly [ADP-ribose] polymerase 16.

Background: Poly(ADP-ribosylation) is a method of DNA damage-dependent posttranslational modification that helps to rescue injured proliferating cells from cell death. The PARP (poly(ADP-ribose) polymerase) proteins comprise a superfamily of enzymes that functionally modify histones and other nuclear proteins, thereby preventing cell death. PARPs use NAD+ as a substrate to catalytically transfer ADP-ribose residues onto protein acceptors, a process that, when repeated multiple times, leads to the formation of poly(ADPribose) chains on the protein. The presence of these chains alters the function of the target protein and promotes cell survival. PARP proteins are implicated in a variety of diseases, including cancer, neurodegenerative and inflammatory disorders. PARP-16 is a 322 amino acid poly (ADP-ribose) polymerase protein localized to the membrane. Expressed as three isoforms produced by alternative splicing, PARP-16 contains one PARP catalytic domain.

ID gène: 54956

UniProt: Q8N5Y8