TRAF2 anticorps (C-Term)

N° du produit ABIN501020

Détail du produit anti-TRAF2 anticorps

Antigène: TRAF2 (TNF Receptor-Associated Factor 2 (TRAF2))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRAF2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects TRAF2 at C-term.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogène: TRAF2 antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human TRAF2.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur TRAF2

Antigène: TRAF2 (TNF Receptor-Associated Factor 2 (TRAF2))

Autre désignation: TRAF2 / TRAP3 (TRAF2 Produits)

Synonymes: anticorps MGC:45012, anticorps TRAP, anticorps TRAP3, anticorps TANK, anticorps AI325259, anticorps TNF-receptor-associated factor 2, anticorps conjugal transfer protein TraF, anticorps TNF receptor associated factor 2, anticorps TNF receptor-associated factor 2, anticorps Tnf receptor-associated factor 2, anticorps LOC661716, anticorps traF2, anticorps TRAF2, anticorps Traf2

Sujet: Tumor necrosis factor (TNF) receptor associated factors (TRAFs) were initially discovered as adaptor proteins that link the TNF receptor superfamily to signaling pathways and are thus important regulators of cell death and cellular response to stress (1). TRAF proteins share a homology region that allows them to bind to cell receptors and other TRAF proteins, causing the activation of different signal cascades depending on the TRAFs involved. For example, TRAF2 and TRAF3 directly bind to the CD40, a TNF receptor superfamily member involved in inducing B cell immunity (2), and are critical for NF-kappaB activation in mouse B lymphocytes (3). TRAF2 along with TRAF6 has also been shown to be required for CD40 signaling in nonhemopoietic cells (4). TRAF2 also interacts with the TRFR superfamily member lymphotoxin-b receptor (LTbR) in association with TRAF3 and the apoptosis inhibitors cIAP1 and Smac (5).Synonyms: TNF receptor-associated factor 2, Tumor necrosis factor type 2 receptor-associated protein 3

ID gène: 7186

NCBI Accession: NP_066961

Pathways: Signalisation NF-kappaB, Apoptose, Caspase Cascade in Apoptosis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Unfolded Protein Response, S100 Proteins