RBCK1 anticorps (AA 121-333)

N° du produit ABIN5027252

Détail du produit anti-RBCK1 anticorps

Antigène: RBCK1 (RanBP-Type and C3HC4-Type Zinc Finger Containing 1 (RBCK1))

Épitope: AA 121-333

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RBCK1 est non-conjugé

Application: Western Blotting (WB)

Purification: Protein A Chromatography

Immunogène: A partial length recombinant HOIL-1L/RBCK1 protein (amino acids 121-333) was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: WB: 2-4 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur RBCK1

Antigène: RBCK1 (RanBP-Type and C3HC4-Type Zinc Finger Containing 1 (RBCK1))

Autre désignation: HOIL-1L/RBCK1 (RBCK1 Produits)

Synonymes: anticorps RBCK1, anticorps C20orf18, anticorps HOIL-1, anticorps HOIL1, anticorps RBCK2, anticorps RNF54, anticorps UBCE7IP3, anticorps XAP3, anticorps XAP4, anticorps ZRANB4, anticorps C20ORF18, anticorps AL033326, anticorps HOIL-1L, anticorps UIP28, anticorps Ubce7ip3, anticorps Pkcbpb15, anticorps zgc:91964, anticorps SHANK-associated RH domain interactor, anticorps RANBP2-type and C3HC4-type zinc finger containing 1, anticorps ranBP-type and C3HC4-type zinc finger-containing protein 1, anticorps RanBP-type and C3HC4-type zinc finger containing 1, anticorps SHARPIN, anticorps RBCK1, anticorps LOC100411512, anticorps Rbck1, anticorps rbck1

Sujet: RBCK1 (RanBP-type and C3HC4-type zinc finger containing 1) is a transcription factor belonging to the RING-IBR protein family. It shuttles between the nucleus and cytoplasm, possessing both the nuclear export and localization signals within its amino acid sequence. RBCK1 deficiency causes polyglucosan storage myopathy associated with progressive muscle weakness and cardiomyopathy. RBCK1 negatively regulates the cellular antiviral response. RBCK1 regulates cell cycle progression and proliferation of ERalpha (estrogen receptor alpha)-positive breast cancer cells by supporting transcription of ERalpha and cyclin B1.

Poids moléculaire: 58 kDa

ID gène: 10616

UniProt: Q9BYM8