KLF4 anticorps (AA 1-300)

N° du produit ABIN5027333

Détail du produit anti-KLF4 anticorps

Antigène: KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Épitope: AA 1-300

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLF4 est non-conjugé

Application: Western Blotting (WB)

Purification: Protein A Chromatography

Immunogène: A partial length recombinant KLF4 protein (amino acids 1-300) was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: WB: 2-4 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur KLF4

Antigène: KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Autre désignation: KLF4/GKLF (KLF4 Produits)

Synonymes: anticorps EZF, anticorps GKLF, anticorps Gklf, anticorps Zie, anticorps KLF4, anticorps biklf, anticorps biklf-A, anticorps Kruppel like factor 4, anticorps Kruppel-like factor 4 (gut), anticorps Kruppel-like factor 4, anticorps Kruppel-like factor 4 (gut) L homeolog, anticorps KLF4, anticorps Klf4, anticorps klf4, anticorps klf4.L

Sujet: Kruppel like factor 4 (KLF4) which are also called as gun enriched kruppel like factors (GKLF) is a member of SP/KLF family of zinc transcription factors that are involved in numerous important cellular processes, such as, proliferation, inflammation, apoptosis and somatic cell reprogramming. The Kruppel zinc finger transcription factor was initially identified in Drosophila as a segmented gene. This protein is found to inhibit cell proliferation by functioning as a cell cycle checkpoint protein that leads to activation of transcription of the cyclin-dependent kinase inhibitor. Clinically KLF4 plays a role in the pathogenesis of esophageal cancer and malaria. It has five isoform that are produced by alternate splicing. Expression of KLF4 is highly enriched in the post replicative epithelial cells of the intestine, skin and thymus.

Poids moléculaire: 55 kDa

ID gène: 9314

UniProt: O43474

Pathways: Peptide Hormone Metabolism, Stem Cell Maintenance