GBL anticorps (AA 100-320)

N° du produit ABIN5027338

L’anticorps Lapin Polyclonal anti-GBL a été validé pour WB. Il convient pour détecter GBL dans des échantillons de Humain.

Aperçu rapide pour GBL anticorps (AA 100-320) (ABIN5027338)

Antigène: GBL (G protein beta subunit-like (GBL))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GBL est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GBL anticorps

Épitope: AA 100-320

Purification: Protein A Chromatography

Immunogène: A partial length recombinant LST8/GBL protein (amino acids 100-320) was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: WB: 1-3 μg/mL.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur GBL

Antigène: GBL (G protein beta subunit-like (GBL))

Autre désignation: LST8/GBL

Sujet: MLST8 or GbL (G protein beta protein subunit-like) is a subunit of mTORC1 and mTORC2 which regulates cell growth and survival. Both mTORC1 and 2 are activated in response to growth factors or amino acids but mTORC2 is most likely insensitive towards nutrients. Within mTORC1, LST8 interacts directly with mTOR and helps to enhance its kinase activity. mTORC1 phosphorylates EIF4EBP1 and thereby releasing it from inhibiting the elongation initiation factor 4E (eiF4E). mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. LST8/GBL more or less ubiquitously expressed with highest levels in skeletal muscle, heart and kidney.

Poids moléculaire: 38 kDa

ID gène: 64223

UniProt: Q9BVC4

Pathways: Signalisation PI3K-Akt, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Autophagy, CXCR4-mediated Signaling Events, BCR Signaling, L'effet Warburg