CLEC9A anticorps (AA 15-218)

N° du produit ABIN5027446

Détail du produit anti-CLEC9A anticorps

Antigène: CLEC9A (C-Type Lectin Domain Family 9, Member A (CLEC9A))

Épitope: AA 15-218

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CLEC9A est non-conjugé

Application: Western Blotting (WB)

Purification: Protein G Chromatography

Immunogène: A partial length recombinant protein ( a.a 15-218) of CLEC9A was used as the immunogen for this antibody.

Clone: ABM23H8

Isotype: IgG1 kappa

Information d'application

Indications d'application: WB: 2-4 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur CLEC9A

Antigène: CLEC9A (C-Type Lectin Domain Family 9, Member A (CLEC9A))

Autre désignation: ClEC9A (CLEC9A Produits)

Synonymes: anticorps 9830005G06Rik, anticorps DNGR-1, anticorps DNGR1, anticorps UNQ9341, anticorps RGD1562513, anticorps C-type lectin domain family 9, member a, anticorps C-type lectin domain containing 9A, anticorps C-type lectin domain family 9, member A, anticorps Clec9a, anticorps CLEC9A

Sujet: CLEC9A is a C-type lectin receptor involved in the sensing and presentation of antigens derived from necrotic cells. It is expressed on the surface of the mouse and human dendritic cell subsets specialized for the uptake and processing of material from dead cells. CLEC9A is expressed at the cell surface as a glycosylated dimer and can mediate endocytosis, but not phagocytosis. It possesses a cytoplasmic immunoreceptor tyrosine-based activation-like motif that can recruit Syk kinase and can induce proinflammatory cytokine production. CLEC9A provides targeted recruitment of the adaptive immune system during infection and can also be utilized to enhance immune responses generated by vaccines.

Poids moléculaire: 44 kDa

ID gène: 283420

UniProt: Q6UXN8