Spectrin beta Chain, Erythrocyte (SPTB) anticorps

N° du produit ABIN534235

Détail du produit

Antigène: Spectrin beta Chain, Erythrocyte (SPTB)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Fonction: Mouse monoclonal antibody raised against native SPTB.

Specificité: This antibody is specific to the 220kD human erythroid beta-spectrin. The protein is also present in the membranes of human skeletal muscle cells. Erythroid spectrins, some other proteins of erythroid cytoskeleton, and the transmembrane protein band 3 are highly specific to erythrocytes and their progenitors. They are more reliable markers for erythroid differentiation than Glycophorin A, the commonly used marker for erythroid differentiation, because Glycophorin A is expressed also in many cell lines otherwise exhibiting mainly megakaryotic charasteristics. Monoclonal antibody to erythroid beta-spectrin is derived from the hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.

Réactivité croisée: Humain

Attributs du produit: Antibody Reactive Against Native Purified Protein.

Immunogène: Native purified human SPTB.

Clone: DB2

Isotype: IgG1

Information d'application

Indications d'application: Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (1 % BSA, 0.09 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 4°C. Do not freeze.

Référence

Auranen, Rapola, Pihko, Haltia, Leivo, Soinila, Virtanen, Kalimo, Anderson, Santavuori, Somer: "Muscle membrane-skeleton protein changes and histopathological characterization of muscle-eye-brain disease." dans: Neuromuscular disorders : NMD, Vol. 10, Issue 1, pp. 16-23, (2000) (PubMed).

Détail du antigène

Antigène: Spectrin beta Chain, Erythrocyte (SPTB)

Autre désignation: Spectrin beta chain (erythrocyte) / SPTB (SPTB Produits)

Synonymes: anticorps AI842465, anticorps D330027P03Rik, anticorps Gm1301, anticorps Spnb-1, anticorps Spnb1, anticorps ja, anticorps jaundiced, anticorps mKIAA4219, anticorps EL3, anticorps HS2, anticorps HSPTB1, anticorps SPH2, anticorps spectrin beta, erythrocytic, anticorps spectrin, beta, erythrocytic, anticorps SPTB, anticorps Sptb

ID gène: 6710

Pathways: Regulation of Actin Filament Polymerization