CD44 anticorps

N° du produit ABIN535461

Détail du produit anti-CD44 anticorps

Antigène: CD44

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD44 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunoprecipitation (IP)

Fonction: Mouse monoclonal antibody raised against native CD44.

Specificité: This antibody reacts with extracellular (N-terminal) domain of standard CD44(Phagocyte glycoprotein 1), a 80-95 KDa transmembrane glycoprotein (hyaladherin family) present on the most of cells and tissues (leukocytes, endothelial cells, mesenchymal cells,etc.), it is negative on platelets and hepatocytes.

Réactivité croisée: Chien, Humain, Porc

Immunogène: Native purified CD44 from African Green Monkey COS-7 cells.

Clone: MEM-263

Isotype: IgG1

Information d'application

Indications d'application: Western Blot (2 μg/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: In PBS, pH 7.4 (0.09 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 4°C. Do not freeze.

Références pour anticorps anti-CD44 (ABIN535461)

Qin, Yang, Xu, Smithc, Xu, Yuan, Li: "Concurrent CD44s and STAT3 expression in human clear cell renal cellular carcinoma and its impact on survival." dans: International journal of clinical and experimental pathology, Vol. 7, Issue 6, pp. 3235-44, (2014) (PubMed).

Li, Tang, Wu, Karnak, Meng, Thompson, Hao, Li, Qiao, Lin, Fuchs, Simeone, Chen, Lawrence, Xu: "HAb18G/CD147 promotes pSTAT3-mediated pancreatic cancer development via CD44s." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 19, Issue 24, pp. 6703-15, (2013) (PubMed).

Subramaniam, Vincent, Gardner, Chan, Dhamko, Jothy: "CD44 regulates cell migration in human colon cancer cells via Lyn kinase and AKT phosphorylation." dans: Experimental and molecular pathology, Vol. 83, Issue 2, pp. 207-15, (2007) (PubMed).

Subramaniam, Gardner, Jothy: "Soluble CD44 secretion contributes to the acquisition of aggressive tumor phenotype in human colon cancer cells." dans: Experimental and molecular pathology, Vol. 83, Issue 3, pp. 341-6, (2007) (PubMed).

Détails sur CD44

Antigène: CD44

Autre désignation: CD44 / PGP-1 / HUTCH-I (CD44 Produits)

Synonymes: anticorps CDW44, anticorps CSPG8, anticorps ECMR-III, anticorps HCELL, anticorps HUTCH-I, anticorps IN, anticorps LHR, anticorps MC56, anticorps MDU2, anticorps MDU3, anticorps MIC4, anticorps Pgp1, anticorps AU023126, anticorps AW121933, anticorps AW146109, anticorps HERMES, anticorps Ly-24, anticorps Pgp-1, anticorps CD44A, anticorps METAA, anticorps RHAMM, anticorps XCD44, anticorps cd44, anticorps cdw44, anticorps cspg8, anticorps ecmr-iii, anticorps hcell, anticorps lhr, anticorps mc56, anticorps mdu2, anticorps mdu3, anticorps mic4, anticorps mutch-i, anticorps pgp1, anticorps CD44 molecule (Indian blood group), anticorps syndecan 4, anticorps CD44 antigen, anticorps CD44 molecule (Indian blood group) S homeolog, anticorps CD44, anticorps SDC4, anticorps Cd44, anticorps cd44.S

ID gène: 960

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling