ATR anticorps (Ser428)

N° du produit ABIN540506

Détail du produit anti-ATR anticorps

Antigène: ATR (ATR serine/threonine kinase (ATR))

Épitope: Ser428

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATR est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit polyclonal antibody raised against synthetic peptide of ATR.

Séquence: GISPK

Specificité: ATR (Ab-428) Antiobdy detects endogenous levels of total ATR protein.

Réactivité croisée: Humain

Attributs du produit: Antibody Reactive Against Synthetic Peptide.

Immunogène: A synthetic peptide (conjugated with KLH) corresponding to residues surrounding S428 of human ATR.

Information d'application

Indications d'application: Immunohistochemistry (1:50-1:100)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: In PBS (without Mg²⁺ and Ca²⁺), 150 mM NaCl, pH 7.4 (50 % glycerol, 0.02 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-ATR (ABIN540506)

Shechter, Costanzo, Gautier: "Regulation of DNA replication by ATR: signaling in response to DNA intermediates." dans: DNA repair, Vol. 3, Issue 8-9, pp. 901-8, (2004) (PubMed).

Zhou, Lu, Wulf, Lu: "Phosphorylation-dependent prolyl isomerization: a novel signaling regulatory mechanism." dans: Cellular and molecular life sciences : CMLS, Vol. 56, Issue 9-10, pp. 788-806, (2001) (PubMed).

Kastan, Lim: "The many substrates and functions of ATM." dans: Nature reviews. Molecular cell biology, Vol. 1, Issue 3, pp. 179-86, (2001) (PubMed).

Détails sur ATR

Antigène: ATR (ATR serine/threonine kinase (ATR))

Autre désignation: ATR (ATR Produits)

Synonymes: anticorps FCTCS, anticorps FRP1, anticorps MEC1, anticorps SCKL, anticorps SCKL1, anticorps ATR serine/threonine kinase, anticorps ataxia telangiectasia and Rad3 related, anticorps ATR, anticorps Atr

ID gène: 545

Pathways: Positive Regulation of Response to DNA Damage Stimulus