APEX1 anticorps

N° du produit ABIN540784

Détail du produit anti-APEX1 anticorps

Antigène: APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APEX1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Fonction: Rabbit polyclonal antibody raised against recombinant APEX1.

Specificité: This antibody is specific to the human APE/ref-1protein.

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: Recombinant protein corresponding to human APEX1.

Information d'application

Indications d'application: Immunocytochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
Immunoprecipitation (7 μg/mL)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In Tris-glycine, 150 mM NaCl (0.05 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-APEX1 (ABIN540784)

Lam, Bussom, Cheng: "Effect of hypoxia on the expression of phosphoglycerate kinase and antitumor activity of troxacitabine and gemcitabine in non-small cell lung carcinoma." dans: Molecular cancer therapeutics, Vol. 8, Issue 2, pp. 415-23, (2009) (PubMed).

Yang, Chen, Zhang, Huang, Zhang: "Virion-associated uracil DNA glycosylase-2 and apurinic/apyrimidinic endonuclease are involved in the degradation of APOBEC3G-edited nascent HIV-1 DNA." dans: The Journal of biological chemistry, Vol. 282, Issue 16, pp. 11667-75, (2007) (PubMed).

Raffoul, Banerjee, Singh-Gupta, Knoll, Fite, Zhang, Abrams, Sarkar, Hillman: "Down-regulation of apurinic/apyrimidinic endonuclease 1/redox factor-1 expression by soy isoflavones enhances prostate cancer radiotherapy in vitro and in vivo." dans: Cancer research, Vol. 67, Issue 5, pp. 2141-9, (2007) (PubMed).

Briegert, Kaina: "Human monocytes, but not dendritic cells derived from them, are defective in base excision repair and hypersensitive to methylating agents." dans: Cancer research, Vol. 67, Issue 1, pp. 26-31, (2007) (PubMed).

Yang, DeBusk, Fukuda, Fingleton, Green-Jarvis, Shyr, Matrisian, Carbone, Lin: "Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis." dans: Cancer cell, Vol. 6, Issue 4, pp. 409-21, (2004) (PubMed).

Détails sur APEX1

Antigène: APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))

Autre désignation: APEX1 / REF-1 (APEX1 Produits)

Synonymes: anticorps apex1, anticorps MGC76280, anticorps MGC79645, anticorps MGC78928, anticorps APE, anticorps APE1, anticorps APEN, anticorps APEX, anticorps APX, anticorps HAP1, anticorps REF1, anticorps Apex, anticorps REF-1, anticorps BAP1, anticorps apex1a, anticorps hm:zehn1532, anticorps wu:fc13d11, anticorps zgc:66204, anticorps Ref-1, anticorps apurinic/apyrimidinic endodeoxyribonuclease 1, anticorps APEX nuclease (multifunctional DNA repair enzyme) 1, anticorps APEX nuclease (multifunctional DNA repair enzyme) 1 L homeolog, anticorps DNA-(apurinic or apyrimidinic site) lyase, anticorps apurinic/apyrimidinic endonuclease 1, anticorps APEX1, anticorps apex1, anticorps apex1.L, anticorps CNG03640, anticorps CNH01280, anticorps nth, anticorps Spirs_4119, anticorps Palpr_0103, anticorps Apex1

ID gène: 328

Pathways: Réparation de l'ADN, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus