GJB2 anticorps (C-Term)

N° du produit ABIN544540

Détail du produit anti-GJB2 anticorps

Antigène: GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GJB2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit polyclonal antibody raised against synthetic peptide of GJB2.

Réactivité croisée: Humain, Souris

Immunogène: A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human GJB2.

Information d'application

Indications d'application: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-100)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-GJB2 (ABIN544540)

Alesutan, Sopjani, Munoz, Fraser, Kemp, Föller, Lang: "Inhibition of connexin 26 by the AMP-activated protein kinase." dans: The Journal of membrane biology, Vol. 240, Issue 3, pp. 151-8, (2011) (PubMed).

Ohtsuka, Yuge, Kimura, Namba, Abe, Van Laer, Van Camp, Usami: "GJB2 deafness gene shows a specific spectrum of mutations in Japan, including a frequent founder mutation." dans: Human genetics, Vol. 112, Issue 4, pp. 329-33, (2003) (PubMed).

Yotsumoto, Hashiguchi, Chen, Ohtake, Tomitaka, Akamatsu, Matsunaga, Shiraishi, Miura, Adachi, Kanzaki: "Novel mutations in GJB2 encoding connexin-26 in Japanese patients with keratitis-ichthyosis-deafness syndrome." dans: The British journal of dermatology, Vol. 148, Issue 4, pp. 649-53, (2003) (PubMed).

Uyguner, Tukel, Baykal, Eris, Emiroglu, Hafiz, Ghanbari, Baserer, Yuksel-Apak, Wollnik: "The novel R75Q mutation in the GJB2 gene causes autosomal dominant hearing loss and palmoplantar keratoderma in a Turkish family." dans: Clinical genetics, Vol. 62, Issue 4, pp. 306-9, (2002) (PubMed).

Détails sur GJB2

Antigène: GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))

Autre désignation: GJB2 / Cx26 (GJB2 Produits)

Synonymes: anticorps ppk, anticorps cx26, anticorps dfna3, anticorps dfnb1, anticorps nsrd1, anticorps dfna3a, anticorps dfnb1a, anticorps MGC53062, anticorps connexin-26, anticorps GJB2, anticorps AI325222, anticorps Cnx26, anticorps Cx26, anticorps Gjb-2, anticorps CXN-26, anticorps CX26, anticorps DFNA3, anticorps DFNA3A, anticorps DFNB1, anticorps DFNB1A, anticorps HID, anticorps KID, anticorps NSRD1, anticorps PPK, anticorps gap junction protein beta 2 L homeolog, anticorps gap junction protein beta 2, anticorps gap junction protein, beta 2, anticorps gjb2.L, anticorps GJB2, anticorps Gjb2

ID gène: 2706

Pathways: Sensory Perception of Sound, Cell-Cell Junction Organization