HTRA2 anticorps (Middle Region)

N° du produit ABIN5514857

Détail du produit anti-HTRA2 anticorps

Antigène: HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HTRA2 est non-conjugé

Application: Western Blotting (WB)

Séquence: TMKVTAGISF AIPSDRLREF LHRGEKKNSS SGISGSQRRY IGVMMLTLSP

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human HTRA2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 23 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HTRA2

Antigène: HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

Autre désignation: HTRA2 (HTRA2 Produits)

Synonymes: anticorps CG8464, anticorps DmHtrA2, anticorps Dmel\\CG8464, anticorps HtrA2/Omi, anticorps Omi, anticorps dOmi, anticorps domi, anticorps htrA2, anticorps omi, anticorps HTRA2, anticorps PRSS25, anticorps OMI, anticorps PARK13, anticorps AI481710, anticorps Prss25, anticorps mnd2, anticorps HTRA2-related serine protease, anticorps HtrA serine peptidase 2, anticorps HtrA2, anticorps HTRA2, anticorps htra2, anticorps Htra2

Sujet: This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.

Alias Symbols: OMI, PARK13, PRSS25

Protein Size: 361

ID gène: 27429

NCBI Accession: NM_013247, NP_037379

Pathways: Positive Regulation of Endopeptidase Activity