PMS1 anticorps (Middle Region)

N° du produit ABIN5515042

Détail du produit anti-PMS1 anticorps

Antigène: PMS1 (PMS1 Postmeiotic Segregation Increased 1 (S. Cerevisiae) (PMS1))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PMS1 est non-conjugé

Application: Western Blotting (WB)

Séquence: PFQNDMHNDE SGKNTDDCLN HQISIGDFGY GHCSSEISNI DKNTKNAFQD

Attributs du produit: This is a rabbit polyclonal antibody against PMS1. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PMS1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PMS1

Antigène: PMS1 (PMS1 Postmeiotic Segregation Increased 1 (S. Cerevisiae) (PMS1))

Autre désignation: PMS1 (PMS1 Produits)

Synonymes: anticorps PMSL1, anticorps si:dz72b14.2, anticorps si:dz164h20.2, anticorps PMS1, anticorps DKFZp468M105, anticorps pms1, anticorps HNPCC3, anticorps hPMS1, anticorps PMS1 homolog 1, mismatch repair system component, anticorps PMS1 homolog 1, mismatch repair system component S homeolog, anticorps PMS1, anticorps Pms1, anticorps pms1, anticorps pms1.S

Sujet: This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.

Alias Symbols: MLH2, PMSL1, hPMS1, HNPCC3

Protein Interaction Partner: UBC, MSH6, MSH2, MLH1, FAN1, USP5, TOP1, SBF1, RFC4, RFC2, RFC1, REV3L, RANGAP1, PSMC1, PPP2R1A, PMS1, PIK3C2A, PGK1, NONO, MOV10, MCM6, IPO5, KPNA2, CYLD, CDK9, CDC5L, CCNT1, BRCA2, ATR, HELB, PSD2, BRIP1, SBF2, MMS19, RNF123, RNF20, IPO9, UBR5, AKAP9, R

Protein Size: 932

ID gène: 5378

NCBI Accession: NM_000534, NP_000525

UniProt: P54277