Vinculin anticorps (C-Term)

N° du produit ABIN5515246

Détail du produit anti-Vinculin anticorps

Antigène: Vinculin (VCL)

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Vinculin est non-conjugé

Application: Western Blotting (WB)

Séquence: QPQMLVAGAT SIARRANRIL LVAKREVENS EDPKFREAVK AASDELSKTI

Attributs du produit: This is a rabbit polyclonal antibody against VINC. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human VINC

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Vinculin

Antigène: Vinculin (VCL)

Autre désignation: VINC (VCL Produits)

Synonymes: anticorps CMD1W, anticorps CMH15, anticorps MV, anticorps MVCL, anticorps VCL, anticorps im:6902790, anticorps hm:zehn2160, anticorps DDBDRAFT_0186762, anticorps DDBDRAFT_0232320, anticorps DDB_0186762, anticorps DDB_0232320, anticorps 9430097D22, anticorps AA571387, anticorps AI462105, anticorps AW545629, anticorps CG3299, anticorps CT11081, anticorps Dmel\\CG3299, anticorps Dmvincp, anticorps EG:103B4.1, anticorps Vin, anticorps Vin2EF, anticorps vinc, anticorps LOC100228062, anticorps vcl-A, anticorps vinculin, anticorps vinculin a, anticorps vinculin A, anticorps Vinculin, anticorps vinculin S homeolog, anticorps VCL, anticorps vcla, anticorps vinA, anticorps Vcl, anticorps Vinc, anticorps CpipJ_CPIJ013873, anticorps Bm1_37935, anticorps vcl, anticorps vcl.S

Sujet: Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.

Alias Symbols: VCL,

Protein Interaction Partner: VCL, UBC, TEKT1, SUMO2, ASB7, CTPS1, GINS3, UBFD1, ISOC1, DCPS, ERP44, PDCD10, FERMT2, YWHAQ, TUBB3, PDIA4, STK24, YWHAZ, YWHAH, YWHAG, YWHAE, XPO1, SNRPF, RAP1GDS1, PPP5C, PPP1R2, PFAS, PDHA1, MSN, HSPA9, HSPA5, GSS, SFN, GNAI3, G6PD, EIF5, ECHS1, TBCB,

Protein Size: 1134

ID gène: 7414

NCBI Accession: NP_054706

UniProt: P18206

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2