UPK1A anticorps (Middle Region)

N° du produit ABIN5515448

Détail du produit anti-UPK1A anticorps

Antigène: UPK1A (Uroplakin 1a (UPK1A))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UPK1A est non-conjugé

Application: Western Blotting (WB)

Séquence: TKQMLTFYSA DTDQGQELTR LWDRVMIEQE CCGTSGPMDW VNFTSAFRAA

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human UPK1A

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur UPK1A

Antigène: UPK1A (Uroplakin 1a (UPK1A))

Autre désignation: UPK1A (UPK1A Produits)

Synonymes: anticorps up1a, anticorps upia, anticorps upka, anticorps tspan21, anticorps MGC81390, anticorps upk1a, anticorps MGC69509, anticorps UPK1A, anticorps wu:fb14a02, anticorps wu:fk84c04, anticorps zgc:136832, anticorps TSPAN21, anticorps UP1A, anticorps UPIA, anticorps UPKA, anticorps 1110031P12Rik, anticorps AU019298, anticorps C87192, anticorps Tspan21, anticorps Upk1, anticorps uroplakin 1A, anticorps uroplakin 1A L homeolog, anticorps uroplakin 1a, anticorps UPK1A, anticorps upk1a.L, anticorps upk1a, anticorps Upk1a

Sujet: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression. Alternative splicing results in multiple transcript variants of this gene.

Alias Symbols: UP1A, UPIA, UPKA, TSPAN21

Protein Size: 167

ID gène: 11045

NCBI Accession: NM_001281443, NP_001268372

UniProt: O00322