Neurexin 1 anticorps (C-Term)

N° du produit ABIN5515513

Détail du produit anti-Neurexin 1 anticorps

Antigène: Neurexin 1 (NRXN1)

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Neurexin 1 est non-conjugé

Application: Western Blotting (WB)

Séquence: RDEGSYHVDE SRNYISNSAQ SNGAVVKEKQ PSSAKSSNKN KKNKDKEYYV

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human NRXN1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 29 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Neurexin 1

Antigène: Neurexin 1 (NRXN1)

Autre désignation: NRXN1 (NRXN1 Produits)

Synonymes: anticorps Hs.22998, anticorps PTHSL2, anticorps SCZD17, anticorps CG7050, anticorps CT21808, anticorps Dmel\\CG7050, anticorps Nrx, anticorps Nrx1, anticorps dnrx, anticorps dnrx-1, anticorps nrx, anticorps Nrxn1b, anticorps NRXN1, anticorps Nrx-1, anticorps GB13455, anticorps GB18754, anticorps 1700062G21Rik, anticorps 9330127H16Rik, anticorps A230068P09Rik, anticorps mKIAA0578, anticorps neurexin 1, anticorps Neurexin 1, anticorps neurexin I, anticorps neurexin 1b, anticorps neurexin 1a, anticorps NRXN1, anticorps Nrx-1, anticorps Nrxn1, anticorps nrxn1, anticorps nrxn1b, anticorps nrxn1a

Sujet: This gene encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are cell-surface receptors that bind neuroligins to form Ca(2+)-dependent neurexin/neuroligin complexes at synapses in the central nervous system. This complex is required for efficient neurotransmission, and is involved in the formation of synaptic contacts. Three members of this gene family have been studied in detail and are estimated to generate over 3,000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member. Recently, a third promoter (gamma) was identified for this gene in the 3' region. The RefSeq project has decided to create only a few representative transcript variants of the multitude that are possible. Mutations in this gene are associated with Pitt-Hopkins-like syndrome-2.

Alias Symbols: PTHSL2, SCZD17, Hs.22998

Protein Size: 396

ID gène: 9378

NCBI Accession: NM_004801, NP_620072

UniProt: A4FVB9

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development