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PABPN1 anticorps (C-Term)
PABPN1
Reactivité: Humain
WB
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN5515697
Détail du produit anti-PABPN1 anticorps
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Antigène
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PABPN1
(Poly A Binding Protein Nuclear 1 (PABPN1))
Épitope
Tous les épitopes à travers PABPN1 Anticorps.
C-Term
Reactivité
Toutes les réactivités sur PABPN1 Anticorps
Humain
Hôte
Toutes les hôtes sur PABPN1 Anticorps
Lapin
Clonalité
Toutes les clonalités sur PABPN1 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers PABPN1 Anticorps
Cet anticorp PABPN1 est non-conjugé
Application
Tous les applications à travers PABPN1 Anticorps.
Western Blotting (WB)
Séquence
NRPGISTTDR GFPRARYRAR TTNYNSSRSR FYSGFNSRPR GRVYRGRARA
Purification
Affinity purified
Immunogène
The immunogen is a synthetic peptide directed towards the C terminal region of human PABPN1
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 16 % sucrose.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Détails sur PABPN1
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Antigène
PABPN1
(Poly A Binding Protein Nuclear 1 (PABPN1))
Autre désignation
PABPN1 (PABPN1 Produits )
Synonymes
anticorps OPMD, anticorps PAB2, anticorps PABII, anticorps PABP-2, anticorps PABP2, anticorps Pabp3, anticorps mPABII, anticorps ARABIDOPSIS POLY(A) BINDING 2, anticorps ATPAB2, anticorps F28A23.130, anticorps F28A23_130, anticorps POLY(A) BINDING PROTEIN 2, anticorps POLY(A)-BINDING PROTEIN 2, anticorps poly(A) binding protein 2, anticorps opmd, anticorps pab2, anticorps pabp2, anticorps pabpii, anticorps pabpn1, anticorps Pabpn1, anticorps Poly(A)-binding protein 2, anticorps fb19c03, anticorps wu:fb17e03, anticorps wu:fb18c06, anticorps wu:fb19c03, anticorps zgc:85979, anticorps zgc:92452, anticorps poly(A) binding protein nuclear 1, anticorps poly(A) binding protein, nuclear 1, anticorps poly(A) binding protein 2, anticorps poly(A) binding protein, nuclear 1 S homeolog, anticorps poly(A) binding protein, nuclear 1 L homeolog, anticorps polyadenylate-binding protein 2, anticorps poly(A) binding protein Pab2, anticorps PABPN1, anticorps Pabpn1, anticorps PAB2, anticorps pabpn1.S, anticorps pabpn1.L, anticorps LOC100728725, anticorps pab2, anticorps pabpn1
Sujet
This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene. Alias Symbols: OPMD, PAB2, PABII, PABP2, PABP-2, Protein Size: 333
ID gène
8106
NCBI Accession
NM_001199839 , NP_004634
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