CNTNAP2 anticorps (Middle Region)

N° du produit ABIN5515940

Détail du produit anti-CNTNAP2 anticorps

Antigène: CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CNTNAP2 est non-conjugé

Application: Western Blotting (WB)

Séquence: LRYNFQAPAT NARDSSSRVD NAPDQQNSHP DLAQEEIRFS FSTTKAPCIL

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CNTNAP2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CNTNAP2

Antigène: CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))

Autre désignation: CNTNAP2 (CNTNAP2 Produits)

Synonymes: anticorps AUTS15, anticorps CASPR2, anticorps CDFE, anticorps NRXN4, anticorps PTHSL1, anticorps 5430425M22Rik, anticorps Caspr2, anticorps mKIAA0868, anticorps CASPR, anticorps MGC145769, anticorps MGC147944, anticorps MGC147981, anticorps contactin associated protein like 2, anticorps contactin associated protein-like 2, anticorps contactin associated protein like 2b, anticorps CNTNAP2, anticorps Cntnap2, anticorps cntnap2b, anticorps cntnap2

Sujet: This gene encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons. This gene encompasses almost 1.5 % of chromosome 7 and is one of the largest genes in the human genome. It is directly bound and regulated by forkhead box protein P2 (FOXP2), a transcription factor related to speech and language development. This gene has been implicated in multiple neurodevelopmental disorders, including Gilles de la Tourette syndrome, schizophrenia, epilepsy, autism, ADHD and mental retardation

Alias Symbols: CDFE, NRXN4, AUTS15, CASPR2, PTHSL1

Protein Size: 328

ID gène: 26047

NCBI Accession: NM_014141, NP_054860

UniProt: A0A0J9YYA0