VPS72 anticorps (N-Term)

N° du produit ABIN5516202

Détail du produit anti-VPS72 anticorps

Antigène: VPS72 (Vacuolar Protein Sorting 72 Homolog (S. Cerevisiae) (VPS72))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VPS72 est non-conjugé

Application: Western Blotting (WB)

Séquence: GLLEAEEEDE FYQTTYGGFT EESGDDEYQG DQSDTEDEVD SDFDIDEGDE

Attributs du produit: This is a rabbit polyclonal antibody against VPS72. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human VPS72

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur VPS72

Antigène: VPS72 (Vacuolar Protein Sorting 72 Homolog (S. Cerevisiae) (VPS72))

Autre désignation: VPS72 (VPS72 Produits)

Synonymes: anticorps CG4621, anticorps Dmel\\CG4621, anticorps dYL-1, anticorps vps72, anticorps MGC82727, anticorps Vps72, anticorps YL-1, anticorps ACYPI009531, anticorps Tcfl1, anticorps CFL1, anticorps Swc2, anticorps TCFL1, anticorps YL1, anticorps si:dkeyp-24a7.1, anticorps CG4621 gene product from transcript CG4621-RB, anticorps vacuolar protein sorting 72 homolog L homeolog, anticorps potential vacuolar protein sorting protein, anticorps vacuolar protein sorting 72 homolog, anticorps vacuolar protein sorting-associated protein 72 homolog, anticorps vacuolar protein sorting 72, anticorps vacuolar protein sorting 72 homolog S homeolog, anticorps vacuolar protein sorting 72 homolog (S. cerevisiae), anticorps YL-1, anticorps vps72.L, anticorps VPS72, anticorps Vps72, anticorps vps72.S, anticorps vps72

Sujet: The protein encoded by this gene is a shared subunit of two multi-component complexes, the histone acetyltransferase complex TRRAP/TIP60 as well as the chromatin remodeling SRCAP-containing complex. The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation, double strand DNA break repair and apoptosis. The SRCAP-containing complex catalyzes the exchange of histone H2A with the histone variant Htz1 (H2AFZ) into nucleosomes. This protein may be responsible for binding H2AFZ, which has a role in chromosome segregation. This protein may also have a role in regulating long-term hematopoietic stem cell activity. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

Alias Symbols: TCFL1, YL1

Protein Size: 364

ID gène: 6944

NCBI Accession: NP_005988

UniProt: Q15906

Pathways: Stem Cell Maintenance