WAPAL anticorps (Middle Region)

N° du produit ABIN5516204

Détail du produit anti-WAPAL anticorps

Antigène: WAPAL (Wings Apart-Like Protein Homolog (WAPAL))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WAPAL est non-conjugé

Application: Western Blotting (WB)

Séquence: KSKKDVKLEF FGFEDHETGG DEGGSGSSNY KIKYFGFDDL SESEDDEDDD

Attributs du produit: This is a rabbit polyclonal antibody against WAPL. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Human WAPL

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur WAPAL

Antigène: WAPAL (Wings Apart-Like Protein Homolog (WAPAL))

Autre désignation: WAPL (WAPAL Produits)

Synonymes: anticorps RGD1308960, anticorps FOE, anticorps KIAA0261, anticorps WAPL, anticorps 2410073G16, anticorps A530089A20Rik, anticorps BC037674, anticorps mKIAA0261, anticorps mWAPL, anticorps WAPL cohesin release factor, anticorps Wapl, anticorps WAPL, anticorps wapl

Sujet: WAPL is a regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin. It is involved in both sister chromatid cohesion during interphase and sister- chromatid resolution during early stages of mitosis. It couples DNA replication to sister chromatid cohesion. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair.

Alias Symbols: WAPAL, FOE, KIAA0261, WAPL,

Protein Interaction Partner: UBC, RPA3, RPA2, RPA1, XRN1, PDS5A, SMC3, VCP, VPS16, WRAP53, USP15, USP10, NSMCE2, ELAVL1, SUMO2, RAD21, ARAP1, Stag2, WAPAL, PDS5B, STAG1, SMC1A, SRRM1,

Protein Size: 1190

ID gène: 23063

NCBI Accession: NP_055860

UniProt: Q7Z5K2

Pathways: Chromatin Binding