FBXO22 anticorps (Middle Region)

N° du produit ABIN5516515

Détail du produit anti-FBXO22 anticorps

Antigène: FBXO22 (F-Box Protein 22 (FBXO22))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXO22 est non-conjugé

Application: Western Blotting (WB)

Séquence: VVTPMGSGSN RPQEIEIGES GFALLFPQIE GIKIQPFHFI KDPKNLTLER

Attributs du produit: This is a rabbit polyclonal antibody against FBX22. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Human FBX22

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FBXO22

Antigène: FBXO22 (F-Box Protein 22 (FBXO22))

Autre désignation: FBX22 (FBXO22 Produits)

Synonymes: anticorps FBXO22, anticorps DKFZp469L0535, anticorps fbxo22, anticorps MGC146708, anticorps si:busm1-132m23.3, anticorps FBX22, anticorps FISTC1, anticorps 0610033L19Rik, anticorps 1600016C16Rik, anticorps F-box protein 22, anticorps FBXO22, anticorps fbxo22, anticorps Fbxo22

Sujet: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and, as a transcriptional target of the tumor protein p53, is thought to be involved in degradation of specific proteins in response to p53 induction. Alternative splicing results in multiple transcript variants.

Alias Symbols: FBXO22, FBX22,

Protein Interaction Partner: Srr, UBC, CUL1, SKP1, NEDD8, COPS5, COPS6, RBX1,

Protein Size: 403

ID gène: 26263

NCBI Accession: NP_671717

UniProt: Q8NEZ5

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development