LAIR1 anticorps (C-Term)

N° du produit ABIN5516675

Détail du produit anti-LAIR1 anticorps

Antigène: LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LAIR1 est non-conjugé

Application: Western Blotting (WB)

Séquence: HRQNQIKQGP PRSKDEEQKP QQRPDLAVDV LERTADKATV NGLPEKDRET

Attributs du produit: This is a rabbit polyclonal antibody against LAIR1. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human LAIR1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur LAIR1

Antigène: LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))

Autre désignation: LAIR1 (LAIR1 Produits)

Synonymes: anticorps 5133400O11Rik, anticorps BB115266, anticorps D7Bwg0421e, anticorps Lair-1, anticorps mLair-1, anticorps CD305, anticorps LAIR-1, anticorps leukocyte-associated Ig-like receptor 1, anticorps leukocyte associated immunoglobulin like receptor 1, anticorps leukocyte-associated immunoglobulin-like receptor 1, anticorps Lair1, anticorps LAIR1

Sujet: The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants.

Alias Symbols: LAIR1, CD305,

Protein Interaction Partner: LAIR1, APP, UBC, PTPN6, PTPN11, CSK,

Protein Size: 287

ID gène: 3903

UniProt: Q6GTX8