EYA4 anticorps (Middle Region)

N° du produit ABIN5516718

Détail du produit anti-EYA4 anticorps

Antigène: EYA4 (Eyes Absent Homolog 4 (EYA4))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EYA4 est non-conjugé

Application: Western Blotting (WB)

Séquence: QESLPGLTNQ PGEFDTMQSP STPIKDLDER TCRSSGSKSR GRGRKNNPSP

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human EYA4

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur EYA4

Antigène: EYA4 (Eyes Absent Homolog 4 (EYA4))

Autre désignation: EYA4 (EYA4 Produits)

Synonymes: anticorps B130023L16Rik, anticorps CMD1J, anticorps DFNA10, anticorps EYA transcriptional coactivator and phosphatase 4, anticorps Eya4, anticorps EYA4

Sujet: This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator through its protein phosphatase activity, and it may be important for eye development, and for continued function of the mature organ of Corti. Mutations in this gene are associated with postlingual, progressive, autosomal dominant hearing loss at the deafness, autosomal dominant non-syndromic sensorineural 10 locus. The encoded protein is also a putative oncogene that mediates DNA repair, apoptosis, and innate immunity following DNA damage, cellular damage, and viral attack. Defects in this gene are also associated with dilated cardiomyopathy 1J. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Alias Symbols: CMD1J, DFNA10

Protein Size: 585

ID gène: 2070

NCBI Accession: NM_001301012, NP_004091

Pathways: Sensory Perception of Sound