GSTM4 anticorps (Middle Region)

N° du produit ABIN5516880

Détail du produit anti-GSTM4 anticorps

Antigène: GSTM4 (Glutathione S-Transferase mu 4 (GSTM4))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSTM4 est non-conjugé

Application: Western Blotting (WB)

Séquence: EYTDSSYEEK KYTMGDAPDY DRSQWLNEKF KLGLDFPNLP YLIDGAHKIT

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human GSTM4

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GSTM4

Antigène: GSTM4 (Glutathione S-Transferase mu 4 (GSTM4))

Autre désignation: GSTM4 (GSTM4 Produits)

Synonymes: anticorps GSTM4-4, anticorps GTM4, anticorps 1110004G14Rik, anticorps GSTM7-7, anticorps Gstb-4, anticorps Gstb4, anticorps glutathione S-transferase mu 4, anticorps glutathione S-transferase, mu 4, anticorps GSTM4, anticorps Gstm4

Sujet: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. Multiple transcript variants, each encoding a distinct protein isoform, have been identified.

Alias Symbols: GTM4, GSTM4-4,

Protein Size: 218

ID gène: 2948

NCBI Accession: NM_000850, NP_000841

UniProt: Q03013