Complement C2 anticorps (Middle Region)

N° du produit ABIN5517107

Détail du produit anti-Complement C2 anticorps

Antigène: Complement C2

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Complement C2 est non-conjugé

Application: Western Blotting (WB)

Séquence: FILQDTKALH QVFEHMLDVS KLTDTICGVG NMSANASDQE RTPWHVTIKP

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human C2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 29 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Complement C2

Antigène: Complement C2

Autre désignation: C2 (Complement C2 Produits)

Synonymes: anticorps CO2, anticorps complement C2, anticorps complement component 2 (within H-2S), anticorps C2

Sujet: Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.

Alias Symbols: CO2, ARMD14

Protein Size: 353

ID gène: 717

NCBI Accession: NP_000054

UniProt: A0A0G2JK28