MAML1 anticorps (Middle Region)

N° du produit ABIN5517154

Détail du produit anti-MAML1 anticorps

Antigène: MAML1 (Mastermind-Like 1 (MAML1))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAML1 est non-conjugé

Application: Western Blotting (WB)

Séquence: VNKSSPRPGG PYLQPSHVNL LSHQPPSNLN QNSANNQGSV LDYGNTKPLS

Attributs du produit: This is a rabbit polyclonal antibody against MAML1. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Human MAML1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MAML1

Antigène: MAML1 (Mastermind-Like 1 (MAML1))

Autre désignation: MAML1 (MAML1 Produits)

Synonymes: anticorps mam1, anticorps mam-1, anticorps xmam1, anticorps MAML1, anticorps AI644666, anticorps AW743257, anticorps D930008C07Rik, anticorps Mam-1, anticorps Mam1, anticorps mKIAA0200, anticorps mastermind like transcriptional coactivator 1 L homeolog, anticorps mastermind like transcriptional coactivator 1, anticorps mastermind like 1 (Drosophila), anticorps mastermind-like transcriptional coactivator 1, anticorps maml1.L, anticorps MAML1, anticorps Maml1

Sujet: This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway.

Alias Symbols: MAML1 {ECO:0000312|HGNC:HGNC:13632

Protein Interaction Partner: Su(H), NOTCH1, RBPJ, PBRM1, PHF8, SMARCA4, HDAC9, PIAS1, MAML1, CDK8, EP300, NOTCH3, NOTCH2, CREBBP, NOTCH4, MAML2, MAML3,

Protein Size: 1016

ID gène: 9794

NCBI Accession: NP_055572

UniProt: Q92585

Pathways: Signalisation Notch, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development