Tescalcin anticorps (N-Term)

N° du produit ABIN5517455

Détail du produit anti-Tescalcin anticorps

Antigène: Tescalcin (TESC)

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Tescalcin est non-conjugé

Application: Western Blotting (WB)

Séquence: LELNPIRSKI VRAFFDNRNL RKGPSGLADE INFEDFLTIM SYFRPIDTTM

Attributs du produit: This is a rabbit polyclonal antibody against TESC. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human TESC

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Tescalcin

Antigène: Tescalcin (TESC)

Autre désignation: TESC (TESC Produits)

Synonymes: anticorps TSC, anticorps chp3, anticorps CHP3, anticorps 1010001A17Rik, anticorps 2410011K10Rik, anticorps TE-1, anticorps RGD1566317, anticorps tescalcin, anticorps tescalcin L homeolog, anticorps tesc, anticorps TESC, anticorps Tesc, anticorps tesc.L

Sujet: TESC functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. It promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane. It promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. It is essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. It is also involved in granulocytic differentiation in a ERK-dependent manner. It inhibits the phosphatase activity of calcineurin.

Alias Symbols: TESC, CHP3,

Protein Interaction Partner: WBP11, UBC, CCDC91, HMG20A, TESC, RAI1, DYNLT3, SLC9A1,

Protein Size: 214

ID gène: 54997

NCBI Accession: NP_060369

UniProt: Q96BS2

Pathways: Proton Transport