Neurocan anticorps

N° du produit ABIN5519042

Détail du produit anti-Neurocan anticorps

Antigène: Neurocan (NCAN)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Neurocan est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Neurocan detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Séquence: HENTWIGLND RIVERDFQWT DNTGLQFENW RENQPDNFFA

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Neurocan detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: neurocan
Protein Name: Neurocan core protein

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence of human Neurocan (HENTWIGLNDRIVERDFQWTDNTGLQFENWRENQPDNFFA).

Isotype: IgG

Information d'application

Indications d'application: Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-Neurocan (ABIN5519042)

Wang, Zhang, Zhang, Fan, Shen, Hu, Chen: "Oxygen-glucose deprivation induced glial scar-like change in astrocytes." dans: PLoS ONE, Vol. 7, Issue 5, pp. e37574, (2012) (PubMed).

Détails sur Neurocan

Antigène: Neurocan (NCAN)

Autre désignation: NCAN (NCAN Produits)

Synonymes: anticorps cspg3, anticorps ncan, anticorps si:ch211-123b7.1, anticorps NCAN, anticorps CSPG3, anticorps Cspg3, anticorps C230035B04, anticorps Cspg3-rs, anticorps Tgfbit, anticorps neurocan b, anticorps neurocan, anticorps ncanb, anticorps NCAN, anticorps Ncan

Sujet: Neurocan core protein is a protein that in humans is encoded by the NCAN gene. Neurocan is a member of the lectican / chondroitin sulfate proteoglycan protein families and consists of neurocan core protein and chondroitin sulfate. It is thought to be involved in the modulation of cell adhesion and migration. In the human subjects, it was found that NCAN genotype was strongly associated with manic symptoms but not with depressive symptoms. In the mice, the absence of functional Neurocan resulted in a variety of manic-like behaviors, which could be normalized by administering lithium.

Synonyms: Neurocan core protein, Chondroitin sulfate proteoglycan 3, NCAN, CSPG3, NEUR

ID gène: 1463

UniProt: O14594

Pathways: Glycosaminoglycan Metabolic Process