PAPSS1 anticorps (C-Term)

N° du produit ABIN5530217

Détail du produit anti-PAPSS1 anticorps

Antigène: PAPSS1 (3'-phosphoadenosine 5'-phosphosulfate Synthase 1 (PAPSS1))

Épitope: AA 592-624, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAPSS1 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogène: This PAPSS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 592-624 amino acids from the C-terminal region of human PAPSS1.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur PAPSS1

Antigène: PAPSS1 (3'-phosphoadenosine 5'-phosphosulfate Synthase 1 (PAPSS1))

Autre désignation: PAPSS1 (PAPSS1 Produits)

Synonymes: anticorps ATPSK1, anticorps PAPSS, anticorps SK1, anticorps AI325286, anticorps Asapk, anticorps papss1, anticorps MGC82588, anticorps atpsk1, anticorps papss, anticorps sk1, anticorps PAPSS1, anticorps wu:fc43e12, anticorps zgc:194984, anticorps zgc:194985, anticorps CG8363, anticorps DmPAPSS, anticorps Dmel\\CG8363, anticorps PAPS, anticorps Paps, anticorps l(3)76BDn, anticorps paps, anticorps 3'-phosphoadenosine 5'-phosphosulfate synthase 1, anticorps bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1, anticorps bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2, anticorps PAPS synthetase, anticorps PAPSS1, anticorps Papss1, anticorps papss1, anticorps papss1.L, anticorps LOC100543301, anticorps LOC100637112, anticorps Papss

Sujet: Sulfotransferase (SULT) enzymes catalyze the sulfate conjugation of many drugs, xenobiotic compounds, hormones, and neurotransmitters. 3'-phosphoadenosine 5'-phosphosulfate (PAPS) synthase (PAPSS) catalyzes the biosynthesis of PAPS which serves as the universal sulfonate donor compound for all sulfotransferase reactions. In humans, PAPS is synthesized from adenosine 5-prime triphosphate (ATP) and inorganic sulfate by 2 isoforms, PAPSS1 and PAPSS2 (603005). Bifunctional PAPSS1 is comprised of an N-terminal APS kinase domain, and a C-terminal ATP sulfurylase domain. Full-length protein has significantly less APS kinase activity than the N-terminal fragment, suggesting that the C-terminal domain exerts a regulatory role on the N-terminal APS kinase activity. In humans there are two major isoforms: PAPSS1 and PAPSS2. In brain and skin PAPSS1 is the major isoform, whereas in liver, cartilage and adrenal glands PAPSS2 isoform expression dominates. The predicted 623-amino acid protein is 98 % identical to mouse PAPS synthase. The N-terminal 268-amino acid region of human PAPS synthase resembles APS kinases from other organisms and contains 3 conserved nucleotide-binding motifs.

Poids moléculaire: 71 kDa

ID gène: 9061

UniProt: O43252

Pathways: Glycosaminoglycan Metabolic Process, Ribonucleoside Biosynthetic Process