CBX8 anticorps (C-Term)

N° du produit ABIN5530751

Détail du produit anti-CBX8 anticorps

Antigène: CBX8 (Chromobox Homolog 8 (CBX8))

Épitope: AA 306-337, C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CBX8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CBX8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 306-337 amino acids from the C-terminal region of human CBX8.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur CBX8

Antigène: CBX8 (Chromobox Homolog 8 (CBX8))

Autre désignation: CBX8 (CBX8 Produits)

Synonymes: anticorps cbx8, anticorps MGC147589, anticorps Pc3, anticorps PC3, anticorps RC1, anticorps chromobox 8, anticorps chromobox 8 S homeolog, anticorps chromobox homolog 8a (Pc class homolog, Drosophila), anticorps cbx8, anticorps CBX8, anticorps Cbx8, anticorps cbx8.S, anticorps cbx8a

Sujet: Chromobox homolog 8 (CBX8 or Pc3) is a member of Drosophila Polycomb group gene family. The polycomb group (PcG) genes are essential for maintenance of appropriate expression patterns of developmental master regulators and thus are essential for proper development. Changes in expression of PcG proteins have been associated with cancer. CBX8 is involved in maintaining the transcriptionally repressive state of genes. It modifies chromatin, rendering it heritably changed in its expressibility. Structurally, CBX4 contains 1 chromo domain, which is 40 to 50 amino acids long.

Poids moléculaire: 43 kDa

ID gène: 57332

UniProt: Q9HC52