Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This COL1A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1077-1106 amino acids from the C-terminal region of human COL1A1.
COL1A1
Reactivité: Humain
WB, IHC, ELISA
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Restrictions
For Research Use only
Format
Liquid
Concentration
0.5 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
anticorps OI4, anticorps Col1a-1, anticorps Cola-1, anticorps Cola1, anticorps Mov-13, anticorps Mov13, anticorps COLIA1, anticorps col1a1, anticorps MGC52532, anticorps COL1A1, anticorps COL1A2, anticorps alpha1(I), anticorps cb21, anticorps sb:cb21, anticorps sb:cb384, anticorps wu:fa99c12, anticorps wu:fb02c06, anticorps alpha3(I), anticorps col1a3, anticorps hm:zeh0348, anticorps wu:fa95h05, anticorps wu:fd02a10, anticorps wu:fj59a10, anticorps collagen type I alpha 1 chain, anticorps collagen, type I, alpha 1, anticorps collagen, type I, alpha 1 S homeolog, anticorps collagen alpha-1(I) chain, anticorps collagen type I alpha 2 chain, anticorps collagen, type I, alpha 1a, anticorps collagen 1a1, anticorps collagen, type I, alpha 1b, anticorps COL1A1, anticorps Col1a1, anticorps col1a1.S, anticorps LOC397571, anticorps COL1A2, anticorps col1a1a, anticorps col1a1, anticorps col1a1b
Sujet
This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish].