E2F2 anticorps (AA 258-286)

N° du produit ABIN5531081

Détail du produit anti-E2F2 anticorps

Antigène: E2F2 (E2F Transcription Factor 2 (E2F2))

Épitope: AA 258-286

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp E2F2 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This E2F2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-286 amino acids from the Central region of human E2F2.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur E2F2

Antigène: E2F2 (E2F Transcription Factor 2 (E2F2))

Autre désignation: E2F2 (E2F2 Produits)

Synonymes: anticorps E2F-2, anticorps CG1071, anticorps Dmel\\CG1071, anticorps E2F, anticorps E2F2, anticorps dE2F-2, anticorps dE2F2, anticorps dE2f2, anticorps de2f2, anticorps e2f2, anticorps 9230110J10, anticorps E130207A07, anticorps fb40b03, anticorps wu:fb40b03, anticorps E2F transcription factor 2, anticorps si:ch211-160f23.5, anticorps E2F2, anticorps E2f2, anticorps si:ch211-160f23.5

Sujet: E2F2 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F3, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner, and it exhibits overall 46 % amino acid identity to E2F1. [provided by RefSeq].

Poids moléculaire: 48 kDa

ID gène: 1870

UniProt: Q14209

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases, DNA Replication