EBP anticorps (C-Term)

N° du produit ABIN5531917

Détail du produit anti-EBP anticorps

Antigène: EBP (Emopamil Binding Protein (Sterol Isomerase) (EBP))

Épitope: AA 201-230, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EBP est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This EBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 201-230 amino acids from the C-terminal region of human EBP.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.45 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur EBP

Antigène: EBP (Emopamil Binding Protein (Sterol Isomerase) (EBP))

Autre désignation: EBP (EBP Produits)

Synonymes: anticorps cdpx2, anticorps cho2, anticorps cpx, anticorps cpxd, anticorps zgc:91895, anticorps CDPX2, anticorps CHO2, anticorps CPX, anticorps CPXD, anticorps AI255399, anticorps Pabp, anticorps Td, anticorps mSI, anticorps emopamil binding protein (sterol isomerase), anticorps emopamil binding protein (sterol isomerase) L homeolog, anticorps phenylalkylamine Ca2+ antagonist (emopamil) binding protein, anticorps Ebp, anticorps ebp.L, anticorps ebp, anticorps EBP

Sujet: The protein encoded by this gene is an integral membrane protein of the endoplasmic reticulum. It is a high affinity binding protein for the antiischemic phenylalkylamine Ca2+ antagonist [3H]emopamil and the photoaffinity label [3H]azidopamil. It is similar to sigma receptors and may be a member of a superfamily of high affinity drug-binding proteins in the endoplasmic reticulum of different tissues. This protein shares structural features with bacterial and eukaryontic drug transporting proteins. It has four putative transmembrane segments and contains two conserved glutamate residues which may be involved in the transport of cationic amphiphilics. Another prominent feature of this protein is its high content of aromatic amino acid residues (>23 % ) in its transmembrane segments. These aromatic amino acid residues have been suggested to be involved in the drug transport by the P-glycoprotein. Mutations in this gene cause Chondrodysplasia punctata 2 (CDPX2, also known as Conradi-Hunermann syndrome).

Poids moléculaire: 26 kDa

ID gène: 10682

UniProt: Q15125