CRYGD anticorps (AA 73-101)

N° du produit ABIN5532535

Détail du produit anti-CRYGD anticorps

Antigène: CRYGD (Crystallin, gamma D (CRYGD))

Épitope: AA 73-101

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRYGD est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CRYGD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 73-101 amino acids from the Central region of human CRYGD.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur CRYGD

Antigène: CRYGD (Crystallin, gamma D (CRYGD))

Autre désignation: CRYGD (CRYGD Produits)

Synonymes: anticorps ccp, anticorps caca, anticorps cca3, anticorps cryg4, anticorps cry-g-d, anticorps MGC85594, anticorps CRYGD, anticorps CACA, anticorps CCA3, anticorps CCP, anticorps CRYG4, anticorps CTRCT4, anticorps PCC, anticorps cry-g-D, anticorps Aey4, anticorps Cryg-1, anticorps DGcry-1, anticorps Lop12, anticorps Cryg4, anticorps Len, anticorps crystallin gamma D L homeolog, anticorps crystallin gamma D, anticorps crystallin, gamma D, anticorps crygd.L, anticorps CRYGD, anticorps Crygd

Sujet: Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.

Poids moléculaire: 21 kDa

ID gène: 1421

UniProt: P07320