This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This ARAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-93 amino acids from the N-terminal region of human ARAP2.
ARAP2
Reactivité: Humain
WB, ELISA
Hôte: Lapin
Polyclonal
PE
Indications d'application
For WB starting dilution is: 1:1000
Restrictions
For Research Use only
Format
Liquid
Concentration
0.5 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antigène
ARAP2
(ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 2 (ARAP2))
anticorps CENTD1, anticorps PARX, anticorps Centd1, anticorps Gm148, anticorps mKIAA0580, anticorps ARAP2, anticorps ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2, anticorps arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2, anticorps ARAP2, anticorps Arap2, anticorps LOC100567363
Sujet
The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics.