KLKB1 anticorps (C-Term)

N° du produit ABIN5533087

Détail du produit anti-KLKB1 anticorps

Antigène: KLKB1 (Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1))

Épitope: AA 508-537, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLKB1 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This KLKB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 508-537 amino acids from the C-terminal region of human KLKB1.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.47 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur KLKB1

Antigène: KLKB1 (Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1))

Autre désignation: KLKB1 (KLKB1 Produits)

Synonymes: anticorps KLK3, anticorps PPK, anticorps APS, anticorps Kal-3, anticorps Kal3, anticorps Klk3, anticorps PSA, anticorps KALP15, anticorps Kalp1, anticorps KLKB1, anticorps DKFZp459J2015, anticorps klkb1, anticorps kallikrein B1, anticorps kallikrein B, plasma 1, anticorps plasma kallikrein, anticorps Plasma kallikrein, anticorps kallikrein B, plasma (Fletcher factor) 1, anticorps coagulation factor XI, anticorps kallikrein B1 L homeolog, anticorps KLKB1, anticorps Klkb1, anticorps CpipJ_CPIJ004042, anticorps CpipJ_CPIJ014955, anticorps CpipJ_CPIJ020108, anticorps VAA_02266, anticorps LOC100549617, anticorps klkb1, anticorps klkb1.L

Sujet: Plasma prekallikrein is a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. It is synthesized in the liver and secreted into the blood as a single polypeptide chain. Plasma prekallikrein is converted to plasma kallikrein by factor XIIa by the cleavage of an internal Arg-Ile bond. Plasma kallikrein therefore is composed of a heavy chain and a light chain held together by a disulphide bond. The heavy chain originates from the amino-terminal end of the zymogen and contains 4 tandem repeats of 90 or 91 amino acids. Each repeat harbors a novel structure called the apple domain. The heavy chain is required for the surface-dependent pro-coagulant activity of plasma kallikrein. The light chain contains the active site or catalytic domain of the enzyme and is homologous to the trypsin family of serine proteases. Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients.

Poids moléculaire: 71 kDa

ID gène: 3818

UniProt: P03952

Pathways: Système du Complément, Brown Fat Cell Differentiation