GJC1 anticorps (N-Term)

N° du produit ABIN5534076

Détail du produit anti-GJC1 anticorps

Antigène: GJC1 (Gap Junction Protein, gamma 1, 45kDa (GJC1))

Épitope: AA 89-120, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GJC1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogène: This GJA7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-120 amino acids from the N-terminal region of human GJA7.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.46 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur GJC1

Antigène: GJC1 (Gap Junction Protein, gamma 1, 45kDa (GJC1))

Autre désignation: GJA7 (GJC1 Produits)

Synonymes: anticorps CX45, anticorps GJA7, anticorps cx45, anticorps gja7, anticorps MGC52735, anticorps GJD3, anticorps GJC1, anticorps C130009G16Rik, anticorps Cnx45, anticorps Cx45, anticorps Gja-7, anticorps Gja7, anticorps gap junction protein gamma 1, anticorps gap junction protein gamma 1 L homeolog, anticorps gap junction protein, delta 3, 31.9kDa, anticorps gap junction protein, gamma 1, anticorps Gap junction gamma-1 protein, anticorps GJC1, anticorps gjc1.L, anticorps GJD3, anticorps Gjc1, anticorps gjc1

Sujet: Gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell closely packed transmembrane channels. Proteins, called connexins, purified from fractions of enriched gap junctions from different tissues differ. Connexins are designated by their molecular mass. Another system of nomenclature divides gap junction proteins into 2 categories, alpha and beta, according to sequence similarities at the nucleotide and amino acid levels. For example, CX43 is designated alpha-1 gap junction protein, whereas CX32 and CX26 are called beta-1 and beta-2 gap junction proteins, respectively. This nomenclature emphasizes that CX32 and CX26 are more homologous to each other than either of them is to CX43. Connexins have four transmembrane, three intracellular, and two extracellular regions. Different tissues express different connexins, though tissue specificities overlap, and a given tissue or cell can express several different connexins. Developmental regulation of at least some of the connexin genes has been found. Embryo implantation is regulated in part by temporally changing patterns of expression of connexins in the embryo and the maternal decidua.

Poids moléculaire: 45 kDa

ID gène: 10052

UniProt: P36383

Pathways: Cell-Cell Junction Organization