This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This SERPINB8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 274-301 amino acids from the C-terminal region of human SERPINB8.
SERPINB8
Reactivité: Humain
ELISA
Hôte: Lapin
Polyclonal
HRP
Indications d'application
For WB starting dilution is: 1:1000
Restrictions
For Research Use only
Format
Liquid
Concentration
0.5 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antigène
SERPINB8
(serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 8 (SERPINB8))
anticorps pi8, anticorps cap2, anticorps CAP-2, anticorps CAP2, anticorps NK10, anticorps Spi8, anticorps ovalbumin, anticorps PI8, anticorps serpin family B member 8, anticorps serpin B8, anticorps serpin peptidase inhibitor, clade B (ovalbumin), member 8, anticorps serine (or cysteine) peptidase inhibitor, clade B, member 8, anticorps Serpinb8, anticorps SERPINB8, anticorps LOC607205, anticorps serpinb8, anticorps LOC100424017
Sujet
The superfamily of high molecular weight serine proteinase inhibitors (serpins) regulate a diverse set of intracellular and extracellular processes such as complement activation, fibrinolysis, coagulation, cellular differentiation, tumor suppression, apoptosis, and cell migration. Serpins are characterized by well-conserved a tertiary structure that consists of 3 beta sheets and 8 or 9 alpha helices (Huber and Carrell, 1989 [PubMed 2690952]). A critical portion of the molecule, the reactive center loop connects beta sheets A and C. Protease inhibitor-8 (PI8, SERPINB8) is a member of the ov-serpin subfamily, which, relative to the archetypal serpin PI1 (MIM 107400), is characterized by a high degree of homology to chicken ovalbumin, lack of N- and C-terminal extensions, absence of a signal peptide, and a serine rather than an asparagine residue at the penultimate position (summary by Bartuski et al., 1997 [PubMed 9268635]).