TRADD anticorps (AA 126-151)

N° du produit ABIN5534758

Cet anticorps anti-TRADD Polyclonal Lapin (ABIN5534758) détecte spécifiquement TRADD dans WB, IF, IHC (p) et FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour TRADD anticorps (AA 126-151) (ABIN5534758)

Antigène: TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRADD est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-TRADD anticorps

Épitope: AA 126-151

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This TRADD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-151 amino acids from the Central region of human TRADD.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50

For IF starting dilution is: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.36 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur TRADD

Antigène: TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))

Autre désignation: TRADD

Sujet: The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq].

Poids moléculaire: 34 kDa

ID gène: 8717

UniProt: Q15628

Pathways: Signalisation NF-kappaB, Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Hepatitis C