ZBTB7B anticorps (C-Term)

N° du produit ABIN5534847

Détail du produit anti-ZBTB7B anticorps

Antigène: ZBTB7B (Zinc Finger and BTB Domain Containing 7B (ZBTB7B))

Épitope: AA 440-469, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZBTB7B est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogène: This ZBTB7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 440-469 amino acids from the C-terminal region of human ZBTB7B.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For IF starting dilution is: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur ZBTB7B

Antigène: ZBTB7B (Zinc Finger and BTB Domain Containing 7B (ZBTB7B))

Autre désignation: ZBTB7B (ZBTB7B Produits)

Synonymes: anticorps THPOK, anticorps ZBTB15, anticorps ZFP-67, anticorps ZFP67, anticorps ZNF857B, anticorps c-KROX, anticorps hcKROX, anticorps Thpok, anticorps Zfp67, anticorps c-Krox, anticorps ZBTB7B, anticorps zbtb7b, anticorps MGC130914, anticorps zinc finger and BTB domain containing 7B, anticorps kruppel-related zinc finger protein hcKrox, anticorps ZBTB7B, anticorps Zbtb7b, anticorps zbtb7b

Sujet: ZBTB7B is a transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. ZBTB7B is a transcriptional repressor of the collagen COL1A1 and COL1A2 genes. It may also function as a repressor of fibronectin and possibly other extracellular matrix genes.

Poids moléculaire: 58 kDa

ID gène: 51043

UniProt: O15156