This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This POLR2E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-59 amino acids from the N-terminal region of human POLR2E.
POLR2E
Reactivité: Humain
Hôte: Lapin
Polyclonal
FITC
Indications d'application
For WB starting dilution is: 1:1000
Restrictions
For Research Use only
Format
Liquid
Concentration
0.5 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antigène
POLR2E
(Polymerase (RNA) II (DNA Directed) Polypeptide E, 25kDa (POLR2E))
anticorps MGC68604, anticorps polr2e, anticorps wu:fk97g10, anticorps zgc:101098, anticorps 2410021N14Rik, anticorps 25kDa, anticorps AW208866, anticorps RPB5, anticorps XAP4, anticorps RPABC1, anticorps hRPB25, anticorps hsRPB5, anticorps polymerase (RNA) II (DNA directed) polypeptide E, 25kDa S homeolog, anticorps RNA polymerase II subunit E, anticorps polymerase (RNA) II (DNA directed) polypeptide E, b, anticorps polymerase (RNA) II (DNA directed) polypeptide E, 25kDa, anticorps polymerase (RNA) II (DNA directed) polypeptide E, anticorps DNA-directed RNA polymerases I, II, and III subunit RPABC1, anticorps polr2e.S, anticorps POLR2E, anticorps polr2eb, anticorps polr2e, anticorps Polr2e, anticorps rpb-5
Sujet
This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits. An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit. A pseudogene is located on chromosome 11.