APIP anticorps (AA 111-142)

N° du produit ABIN5535618

Détail du produit anti-APIP anticorps

Antigène: APIP (APAF1 Interacting Protein (APIP))

Épitope: AA 111-142

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APIP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This APIP antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 111-142 amino acids from the Central region of human APIP.

Isotype: Ig Fraction

Information d'application

Indications d'application: For IHC-P starting dilution is: 1:25

For WB starting dilution is: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur APIP

Antigène: APIP (APAF1 Interacting Protein (APIP))

Autre désignation: APIP (APIP Produits)

Synonymes: anticorps APIP2, anticorps CGI29, anticorps MMRP19, anticorps dJ179L10.2, anticorps hAPIP, anticorps CGI-29, anticorps Mmrp19, anticorps RGD1564562, anticorps zgc:103619, anticorps APAF1 interacting protein, anticorps APAF1 interacting protein S homeolog, anticorps APIP, anticorps Apip, anticorps apip, anticorps apip.S

Sujet: Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death.

Poids moléculaire: 27 kDa

ID gène: 51074

UniProt: Q96GX9

Pathways: Methionine Biosynthetic Process