CHRNG anticorps (N-Term)

N° du produit ABIN5536008

Détail du produit anti-CHRNG anticorps

Antigène: CHRNG (Cholinergic Receptor, Nicotinic, gamma (CHRNG))

Épitope: AA 22-50, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHRNG est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CHRNG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-50 amino acids from the N-terminal region of human CHRNG.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur CHRNG

Antigène: CHRNG (Cholinergic Receptor, Nicotinic, gamma (CHRNG))

Autre désignation: CHRNG (CHRNG Produits)

Synonymes: anticorps ACHRG, anticorps Achr-3, anticorps Acrg, anticorps cholinergic receptor nicotinic gamma subunit, anticorps cholinergic receptor, nicotinic gamma L homeolog, anticorps cholinergic receptor, nicotinic, gamma, anticorps cholinergic receptor, nicotinic gamma, anticorps cholinergic receptor, nicotinic, gamma polypeptide, anticorps CHRNG, anticorps chrng.L, anticorps Chrng, anticorps chrng

Sujet: The mammalian muscle-type acetylcholine receptor is a transmembrane pentameric glycoprotein with two alpha subunits, one beta, one delta, and one epsilon (in adult skeletal muscle) or gamma (in fetal and denervated muscle) subunit. This gene, which encodes the gamma subunit, is expressed prior to the thirty-third week of gestation in humans. The gamma subunit of the acetylcholine receptor plays a role in neuromuscular organogenesis and ligand binding and disruption of gamma subunit expression prevents the correct localization of the receptor in cell membranes. Mutations in this gene cause Escobar syndrome and a lethal form of multiple pterygium syndrome. Muscle-type acetylcholine receptor is the major antigen in the autoimmune disease myasthenia gravis.

Poids moléculaire: 58 kDa

ID gène: 1146

UniProt: P07510