KCNA1 anticorps (AA 172-201)

N° du produit ABIN5536325

Détail du produit anti-KCNA1 anticorps

Antigène: KCNA1 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 1 (KCNA1))

Épitope: AA 172-201

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This KCNA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-201 amino acids from the Central region of human KCNA1.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur KCNA1

Antigène: KCNA1 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 1 (KCNA1))

Autre désignation: KCNA1 (KCNA1 Produits)

Synonymes: anticorps AEMK, anticorps EA1, anticorps HBK1, anticorps HUK1, anticorps KV1.1, anticorps MBK1, anticorps MK1, anticorps RBK1, anticorps KCNA1, anticorps AI840627, anticorps Kca1-1, anticorps Kv1.1, anticorps Mk-1, anticorps Shak, anticorps mceph, anticorps Kcna, anticorps Kcpvd, anticorps potassium voltage-gated channel subfamily A member 1, anticorps potassium voltage-gated channel, shaker-related subfamily, member 1, anticorps fragile site, aphidicolin type, common, fra(12)(q24), anticorps KCNA1, anticorps Kcna1, anticorps FRA12E

Sujet: This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).

Poids moléculaire: 56 kDa

ID gène: 3736

UniProt: Q09470