ITM2C anticorps (N-Term)

N° du produit ABIN5536627

Détail du produit anti-ITM2C anticorps

Antigène: ITM2C (Integral Membrane Protein 2C (ITM2C))

Épitope: AA 27-55, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITM2C est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ITM2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-55 amino acids from the N-terminal region of human ITM2C.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.36 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur ITM2C

Antigène: ITM2C (Integral Membrane Protein 2C (ITM2C))

Autre désignation: ITM2C (ITM2C Produits)

Synonymes: anticorps 3110038L02Rik, anticorps BRI3, anticorps Bricd2c, anticorps E25, anticorps E25C, anticorps ITM3, anticorps BRICD2C, anticorps fj35c02, anticorps itm2c, anticorps wu:fj35c02, anticorps zgc:66349, anticorps wu:fj52a04, anticorps zgc:92783, anticorps integral membrane protein 2C, anticorps integral membrane protein 2Cb, anticorps integral membrane protein 2Ca, anticorps Itm2c, anticorps ITM2C, anticorps itm2cb, anticorps itm2ca

Sujet: Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation (By similarity).

Poids moléculaire: 30 kDa

ID gène: 81618

UniProt: Q9NQX7