PTGIS anticorps (C-Term)

N° du produit ABIN5536967

Détail du produit anti-PTGIS anticorps

Antigène: PTGIS (Prostaglandin I2 (Prostacyclin) Synthase (PTGIS))

Épitope: AA 472-500, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTGIS est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogène: This CYP8A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 472-500 amino acids from the C-terminal region of human CYP8A1.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur PTGIS

Antigène: PTGIS (Prostaglandin I2 (Prostacyclin) Synthase (PTGIS))

Autre désignation: CYP8A1 (PTGIS Produits)

Synonymes: anticorps CYP8, anticorps CYP8A1, anticorps PGIS, anticorps PTGI, anticorps Cyp8, anticorps Cyp8a1, anticorps Pgis, anticorps ptgisl, anticorps PTGIS, anticorps prostaglandin I2 synthase, anticorps prostaglandin I2 (prostacyclin) synthase, anticorps prostacyclin synthase, anticorps PTGIS, anticorps Ptgis, anticorps ptgis, anticorps VDBG_06319

Sujet: CYP8A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis.

Poids moléculaire: 57 kDa

ID gène: 5740

UniProt: Q16647