PDIA3 anticorps (C-Term)

N° du produit ABIN5537290

Détail du produit anti-PDIA3 anticorps

Antigène: PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))

Épitope: AA 446-475, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDIA3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogène: This PDIA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 446-475 amino acids from the C-terminal region of human PDIA3.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur PDIA3

Antigène: PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))

Autre désignation: PDIA3 (PDIA3 Produits)

Synonymes: anticorps ER60, anticorps ERp57, anticorps ERp60, anticorps ERp61, anticorps GRP57, anticorps GRP58, anticorps HsT17083, anticorps P58, anticorps PI-PLC, anticorps grp-58, anticorps 58kDa, anticorps Erp, anticorps Grp58, anticorps PDI, anticorps PDI-Q2, anticorps PLC[a], anticorps Plca, anticorps 1, anticorps 25D3-membrane-associated, anticorps sb:cb825, anticorps erp57, anticorps grp58, anticorps pdia3, anticorps protein disulfide isomerase family A member 3, anticorps protein disulfide-isomerase A3, anticorps protein disulfide isomerase associated 3, anticorps protein disulfide isomerase family A, member 3, anticorps protein disulfide isomerase family A member 3 S homeolog, anticorps PDIA3, anticorps Tsp_10062, anticorps Pdia3, anticorps pdia3, anticorps pdia3.S

Sujet: PDIA3 is the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase, however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.

Poids moléculaire: 57 kDa

ID gène: 2923

UniProt: P30101

Pathways: Maintenance of Protein Location, Protein targeting to Nucleus, Cell RedoxHomeostasis