PAAF1 anticorps (N-Term)

N° du produit ABIN5538344

Détail du produit anti-PAAF1 anticorps

Antigène: PAAF1 (Proteasomal ATPase-Associated Factor 1 (PAAF1))

Épitope: AA 109-138, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAAF1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PAAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from the N-terminal region of human PAAF1.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur PAAF1

Antigène: PAAF1 (Proteasomal ATPase-Associated Factor 1 (PAAF1))

Autre désignation: PAAF1 (PAAF1 Produits)

Synonymes: anticorps paaf, anticorps rpn14, anticorps wdr71, anticorps WDR71, anticorps MGC146521, anticorps PAAF, anticorps Rpn14, anticorps proteasomal ATPase associated factor 1 S homeolog, anticorps proteasomal ATPase associated factor 1, anticorps paaf1.S, anticorps PAAF1, anticorps paaf1, anticorps Paaf1

Sujet: PAAF1 inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency.

Poids moléculaire: 42 kDa

ID gène: 80227

UniProt: Q9BRP4